Accession Number:

ADD013456

Title:

Process for the Preparation of Detoxified Polysaccharide-Outer Membrane Protein Complexes, and Their Use as Antibacterial Vaccines.

Descriptive Note:

Patent, Filed 17 Sep 85, patented 17 Nov 87,

Corporate Author:

DEPARTMENT OF THE ARMY WASHINGTON DC

Report Date:

1987-11-17

Pagination or Media Count:

19.0

Abstract:

This invention relates to a novel means for affording treatment and control of infections in animals, including human beings and other mammalian species, which may becaused by gram-negative bacteria. It is based upon the use or administration of immunogenically effective amounts of a detoxified polysaccharide-outer membrane protein complex against infection by the same bacteria from which it has been derived. The term polysaccharide as used herein includes lipopolysaccharides and capsular polysaccharides.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE