A Nucleic Acid Probe and Method for the Detection of Shigella and Enteroinvasive E. coli Bacteria.
DEPARTMENT OF THE ARMY WASHINGTON DC
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This invention relates to nucleic acid probes and a method for the rapid detection of Shigella and enteroinvasive Escherichia coli, the causative agents of bacterial dysentery, by use of a nucleic acid hybridization probe, equivalent to a plasmid DNA region encoding one of 4 specific invasion-associated, peptides of all strains of Shigella and enterinvasive E. coli, in a nucleic acid hybridization reaction with a clinical specimen containing dysentery bacteria.
- Medicine and Medical Research