Liposome Carriers in Leishmaniasis Chemotherapy with 8-Aminoquinoline Derivatives.
DEPARTMENT OF THE ARMY WASHINGTON DC
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An improved method is provided for the chemotherapy of leishmanial infections. An 8-aminoquinoline antileishmanial agent is encapsulated within liposomes and the liposome-encapsulated drug is injected into the body. Subject use of a liposome carrier has produced marked enhancement of the effectiveness of the drug against leishmanial parasites in the liver such as characteristic of infections which are difficult to treat. Author
- Medicine and Medical Research