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Muscle and Liver Carbohydrates: Response to Military Task Performance by Women and Men

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Annual rept. 23 Sep 1999-22 Sep 2000

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During the fourth year we have focused on making significant progress on all specific aims proposed in the original contract. We have made the following progress in the four hypotheses. Hypothesis I We have completed most of the data analysis and found that, unlike men, women work their lower legs harder during the latter stages of exercise than during the first hour. We have developed a 3-D volume filling protocol that significantly improved the presentation quality of MRI data. Hypothesis II We have confirmed that the left biceps depletes glycogen significantly faster in women both menstrual phases than in men po.oo5, follicular p0.0184, luteal . We have refuted our earlier preliminary conclusion, that there is a significant menstrual cycle variation in net liver glycogen depletion rates in our female population. Hypothesis III We have found a trend toward enhanced muscle glycogen recovery when protein is added to post-exercise carbohydrate supplementation. We believe that this is due to a protein-induced increase in insulin secretion. Hypothesis IV We have made no significant progress on this hypothesis. We performed 20 total studies this year, averaging almost two per month. This represents an improvement in subject recruitment. We requested and were granted a no cost extension of this contract, and we are currently continuing to perform studies aimed at improving the statistical significance of the data.

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research
  • Stress Physiology

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