3-D Ultrasound Vascularity Assessment for Breast Cancer Diagnosis
Annual rept. 1 Sep 1997-31 Aug 1998
MICHIGAN UNIV ANN ARBOR
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This project is to improve the diagnosis and management of patients with breast cancer through development and evaluation of 3D ultrasound imaging and quantification techniques emphasizing vascularity. Progress this second year included advances which should increase the sensitivity and specificity of ultrasound imaging in discriminating benign from malignant known masses. Preliminary data analyses were completed on new trials and contributions were made to advance 3D image acquisition, display and quantification. The registration achieved so far in compound and sequential imaging is unexpectedly good and robust. It has promise for an increasing number of applications that could revolutionize the use of ultrasound in medicine, particularly for serial studies. Our new extended 3D field of view imaging appears to greatly increase the changes of achieving these goals. The results to date in image-based slice positioning continue to be impressive, and at least two companies have implemented aspects of the technique, one with clear acknowledgement of our developments. 3D detection and display of lactic ducts has been illustrated in concept, but much more work will be required to show practical, routine utility.
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