Accession Number:

ADB246947

Title:

Clinical and Technical Evaluation of Full-Field Digital Mammography

Descriptive Note:

Annual rept. 30 Dec 1997-29 Dec 1998

Corporate Author:

COLORADO UNIV HEALTH SCIENCES CENTER DENVER

Personal Author(s):

• Hendrick, R. E.

Report Date:

1999-01-01

Pagination or Media Count:

31.0

Abstract:

This report summarizes the work performed in Year 2 of a three-year study to evaluate full-field digital mammography FFDM as a screening tool for breast cancer. Accomplishments during year two include 1 further progress toward optimization of technique factors to maximize low-contrast lesion detection with FFDM, and 2 performance of FFDM in addition to screen-film mammography on over 3,000 women volunteers over the past year, bringing the total number of study participants to 3,961 women at the two screening sites UCHSC and UMMC. Interim clinical results include a statistically significant lower false positive rate with FFDM than with SFM and statistically indistinguishable sensitivities to breast cancer with the two modalities, in part due to the limited number of cancer cases 22 included among study volunteers to date. In Year 3, volunteer accrual will be higher due to increased accrual at UCHSC and UMMC, plus the addition of new study sites at Bethesda Naval Hospital and the University of South Florida.

Descriptors:

• *DIGITAL SYSTEMS
• *BREAST CANCER
• *MAMMOGRAPHY
• CONTRAST
• DETECTION
• CLINICAL MEDICINE
• HOSPITALS
• LESIONS
• LOW INTENSITY

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE