Prospective Analyses of Hormone Levels, Alcohol Intake, and Body Fat Distribution in Relation to Breast Cancer Risk
BRIGHAM AND WOMEN'S HOSPITAL BOSTON MA
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This career development award is allowing me to increase my expertise in the area of hormones, hormonally-related factors and risk of breast cancer. I proposed to prospectively assess plasma hormone levels, alcohol use and body fat distribution in relation to breast cancer risk. In year one of the grant, I received laboratory results for 155 breast cancer cases and 310 matched controls from a case-control study nested within the prospective Nurses Health Study. Several primary estrogens estradiol BOTH FREE AND BOUND FRACTIONS, estrone, estrone sulfate and androgens testosterone, androstenedione, DHEA, DHEAS and prolactin were assayed. Statistical analyses of these data are ongoing and a manuscript is being prepared. Additionally, I have begun the analyses of alcohol intake and risk of breast cancer.
- Medicine and Medical Research