Accession Number:

ADB230950

Title:

Multi-Sensor Fused Interrogation of Brain to Determine ICP Level

Descriptive Note:

Final rept. 12 Nov 1996-11 May 1997

Corporate Author:

ICP TECHNOLOGIES COCKEYSVILLE MD

Personal Author(s):

Report Date:

1997-08-01

Pagination or Media Count:

31.0

Abstract:

To establish the feasibility of non-invasive ICP measurement in a field portable package, a variety of different non-invasive interrogation techniques were evaluated for potential to correlate with elevated ICP. ICP increase was simulated via head-down tilt, jugular occlusion and breath holding. Of the methods tested, spinal CSF pulse wave velocity and ultrasonic location of midline and pineal structures did not meet the requirements. Pulse wave velocity of blood through the head showed potential but further investigation is necessary to determine whether this measurement is truly separating out the superimposed carotid and jugular components of the cranial blood pulse profile. Skull distention measurement also correlated well with increased ICP but the measured displacement could not be distinguished unambiguously from venous engorgement in the fleshy tissue covering the temples. Low frequency acoustics showed excellent potential as a practical and easily implemented means of determining ICP level and showed good correspondence with all means of simulating the pressure elevation. The technique displayed consistent attenuation with ICP rise, in full agreement with the direction and magnitude predicted by our fundamental models. Cadaver studies with the low frequency technique confirmed the attenuation measurement during ICP elevation via simulated perfusion of blood through the head.

Subject Categories:

  • Anatomy and Physiology
  • Electrooptical and Optoelectronic Devices
  • Radio Communications

Distribution Statement:

APPROVED FOR PUBLIC RELEASE