Accession Number:

ADB224562

Title:

Role of Raf-1 Signaling in Breast Cancer - Progression to Estrogen Independent Growth

Descriptive Note:

Annual rept. 15 Jun 95-14 Jun 96

Corporate Author:

GEORGETOWN UNIV WASHINGTON DC

Personal Author(s):

Report Date:

1996-07-01

Pagination or Media Count:

21.0

Abstract:

In order to study the role of Raf-1 kinase signaling in the progression of breast cancer from estrogen-dependent to estrogen-independent growth, we had previously established several clones of MCF-7 cells stably expressing a truncated, constitutively active Raf and examined these clones for their ability to grow in the absence of estrogen.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE