Role of Raf-1 Signaling in Breast Cancer - Progression to Estrogen Independent Growth
Annual rept. 15 Jun 95-14 Jun 96
GEORGETOWN UNIV WASHINGTON DC
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In order to study the role of Raf-1 kinase signaling in the progression of breast cancer from estrogen-dependent to estrogen-independent growth, we had previously established several clones of MCF-7 cells stably expressing a truncated, constitutively active Raf and examined these clones for their ability to grow in the absence of estrogen.
- Anatomy and Physiology
- Medicine and Medical Research