Accession Number:

ADB204477

Title:

Non-Invasive Deep Tissue Oxygenation Sensor.

Descriptive Note:

Final rept. 15 Mar-14 Sep 95 on phase 1,

Corporate Author:

VIXEL INC BROOMFIELD CO

Personal Author(s):

Report Date:

1995-10-01

Pagination or Media Count:

15.0

Abstract:

This Small Business Innovation Research Phase I project proved the feasibility of a compact and low cost instrument to measure tissue oxygenation based on near-infrared NIR spectroscopy. NIR light in the .7-1.1 um range penetrates human tissue to a depth of several centimeters, and is attenuated during transmission by oxyhemoglobin, deoxyhemoglobin, melanin, water and cytochrome aa3, each with its own characteristic absorption spectrum. NIR absorption spectroscopy offers a number of advantages in comparison with other oxygen measurement modalities it is non-invasive, uses non-ionizing radiation, offers high spatial and temporal resolution, and supplies new types of metabolic and functional information for low cost, rapid, bedside diagnostic procedures. The Phase I project determined the most practical means to implement a hand-held NIR spectroscopic oxygenation monitor, specified the components needed, defined the measurement method and assessed the practicality of the instrument for phase II development

Subject Categories:

  • Atomic and Molecular Physics and Spectroscopy
  • Medicine and Medical Research
  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE