Systems to Detect Bacterial Contamination of Banked Blood in a Rapid, Non-Invasive Low Technology Manner. Phase 1.
Final rept. 2 Feb-1 Aug 94,
CHERRYSTONE CORP DEVON PA
Pagination or Media Count:
Sepsis from bacterial contamination of blood is an infrequent event in transfusion medicine however, such an event may lead to a fatal outcome or to other serious consequences. Currently, a rapid, non-invasive, low technology method for the detection of bacterial contamination in banked blood is not available for routine use. The purpose of the work undertaken during Phase I of this project was to examine the feasibility of applying a remote sensor to the detection of a common bacterial metabolite as a marker for microbial contamination of banked blood. Upon spiking whole blood with a series of 10 bacterial species each able to generate the marker at 40 C, a simple remote sensor device was found to change color. The results obtained from this Phase I effort provide scientific proof in support of the concept that a remote colorimetric sensitive sensor can be applied to the detection of microbial contaminants in banked blood. Bacteria, Marker, Colorimetric, Metabolite, Detector, Non-invasive, Banked blood.
- Medicine and Medical Research