Accession Number:

ADB189710

Title:

Systems to Detect Bacterial Contamination of Banked Blood in a Rapid, Non-Invasive Low Technology Manner. Phase 1.

Descriptive Note:

Final rept. 2 Feb-1 Aug 94,

Corporate Author:

CHERRYSTONE CORP DEVON PA

Personal Author(s):

Report Date:

1994-08-25

Pagination or Media Count:

21.0

Abstract:

Sepsis from bacterial contamination of blood is an infrequent event in transfusion medicine however, such an event may lead to a fatal outcome or to other serious consequences. Currently, a rapid, non-invasive, low technology method for the detection of bacterial contamination in banked blood is not available for routine use. The purpose of the work undertaken during Phase I of this project was to examine the feasibility of applying a remote sensor to the detection of a common bacterial metabolite as a marker for microbial contamination of banked blood. Upon spiking whole blood with a series of 10 bacterial species each able to generate the marker at 40 C, a simple remote sensor device was found to change color. The results obtained from this Phase I effort provide scientific proof in support of the concept that a remote colorimetric sensitive sensor can be applied to the detection of microbial contaminants in banked blood. Bacteria, Marker, Colorimetric, Metabolite, Detector, Non-invasive, Banked blood.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE