Drug Development Against Viral Diseases of Military Importance (Directed Synthesis)
Technical Report,01 Mar 1991,31 Dec 1991
SOUTHERN RESEARCH INST BIRMINGHAM AL BIRMINGHAM United States
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A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U. S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. The compounds prepared under this contract included nucleoside analogs and other heterocyclic compounds including 6-azauridine analogs, ribavirin analogs, and 1-substituted 4-acetyl-4-phenylpiperidines. Antiviral synthesis laboratory nucleoside analogs heterocyclic compounds 6-azauridine analogs ribavirin analogs 1-substituted 4-acetyl-4-phenylpiperidines.