Accession Number:

ADB165289

Title:

Preparation of Drugs and Bulk Chemical Compounds for the U.S. Army Drug Development Program.

Descriptive Note:

Annual rept. 15 Mar 91-14 Mar 92,

Corporate Author:

ASH STEVENS INC DETROIT MI

Report Date:

1992-05-27

Pagination or Media Count:

65.0

Abstract:

The purpose of this contract is to provide chemical compounds for the U.S. Army Medical R and D Command. In the 12 months, five assignments were completed. Compounds submitted include a phosphinylpentanoic acid, an 8-aminoquinoline intermediate and three potential metabolites of WR 238605. Preparative work on a large, 2.5 kg lot of WR 238605 was completed also and analysis and characterization of the final product is in progress. 8-Aminoquinoline, Antimalarials, Metabolites, Phosphinylpentanoic acid, Synthesis, RA 5.

Subject Categories:

  • Pharmacology
  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE