Accession Number:

ADB154971

Title:

Synthesis Laboratory for the U.S. Army Medical Research Institute of Infectious Diseases Selection Panel

Descriptive Note:

Annual progress rept. 1 Dec 1989-30 Nov 1990

Corporate Author:

SOUTHERN RESEARCH INST BIRMINGHAM AL

Report Date:

1991-01-14

Pagination or Media Count:

47.0

Abstract:

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. Among the compounds prepared thus far are 1-benzyloxyadenosines, 9-substituted 1-benzyl-oxyadenines, 1,2,4,5, 3,6-tetraazadiphosphorines, substituted imidazoles, selenadiazoles, traizoles, triazolotriazoles, guanidines, pyrazoles, adamantane derivatives, chloroquines, N1-aminonucleosides, allupurinol acyclonucleosides, nucleotides of ribavirin and tiazofurin, and various other heterocyclic compounds.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE