Accession Number:

ADB136918

Title:

Drug Development against Parasitic Diseases: Synthesis of the Antimalarial Agent Qinghaosu and Analogs.

Descriptive Note:

Final rept.,

Corporate Author:

SRI INTERNATIONAL MENLO PARK CA

Personal Author(s):

Report Date:

1988-01-15

Pagination or Media Count:

148.0

Abstract:

Major accomplishments under this contract include an optimized, stereoselective, total synthesis of -artemisinin qinghaosu the synthesis of several analogs of qinghaosu that possess good in vitro antimalarial activity publication of one paper filing of four patents and compilation of data sufficient to warrant the preparation of four manuscripts for publication. Keywords Total synthesis of antimalarial drug Qinghaosu Artemisinin Total synthesis of analogs of Qinghaosu RA 1. KT

Subject Categories:

  • Pharmacology
  • Industrial Chemistry and Chemical Processing

Distribution Statement:

APPROVED FOR PUBLIC RELEASE