Accession Number:

ADB134374

Title:

Determination of the In Vitro and In Vivo Activity of Compounds Tested Against Punta Toro Virus

Descriptive Note:

Annual rept. 1 Dec 1987-30 Nov 1988

Corporate Author:

UTAH STATE UNIV LOGAN

Personal Author(s):

Report Date:

1988-12-20

Pagination or Media Count:

324.0

Abstract:

Partial Contents In Vivo Assessment of Toxicity In Vitro Evaluation of Test Compounds Against Adames Strain and Balliet Strain Punta Toro Virus In Vivo Anti-Punta Toro Virus Activity of AVS Compounds Effect of AVS Compounds on Hepatotropic Infections and Intracerebral Infections in Mice Effect of a Combination of AVS01 and AVS206 on In Vitro Punta Toro Virus Infections Effect of the combination of AVS206 and AVS2776 on In Vivo Punta Toro Virus Infections Effect of the Combination of AVS01 and AVS1754 on In Vivo Punta Toro Virus Infections Effect of a Combination of AVS206 and AVS1767 on In Vivo Punta Toro Virus Infections Effects on Treatment with AVS206 on Delayed Infection Parameters in Punta Toro Virus-Infected Mice Infectivity of Balliet Strain PTV Effect of intravenous Therapy on Intracerebrally Induced Punta Toro Virus infections Induction of Lethal Disease in Mice Using Intranasal Administration of Balliet Strain Punta Toro Virus Punta Toro Virus-Induced Hematologic Effects in C57BL6 Mice Effects of Various Metabolic Precursors on the Anti-Punta Toro Virus Activity of AVS206 Effects of AVS01 and AVS206 on Uptake of Radiolabeled Metabolic Precursors as a Measure of Cytotoxicity Interferon Induction by AVS2776 In Vitro Antiviral Activity of Immunomodulators.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE