Infectious Multiple Drug Resistance in the Enterobacteriaceae
Aunual rept. Jun 1976-May 1977
WASHINGTON UNIV SEATTLE DEPT OF MICROBIOLOGY
Pagination or Media Count:
Tobrymycin-resistant burn wound isolates from five different bacterial genera contained a common 68 x 10 to the 6th power dalton R plasmid that could be transmitted by conjugation to Escherichia coli K-12. It was possible by a variety of newly developed methods to detect, characterize and show molecular identity of this R plasmid in clinical isolates from patients. This study illustrates the usefulness of simple screening methods for studying the molecular epidemiology of R plasmids in the hospital setting or during an epidemic.