The Mesentric Circulation in Diarrheal Diseases.
Final comprehensive rept. 1 Sep 68-30 Jul 73,
TEXAS UNIV MEDICAL SCHOOL AT HOUSTON
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Investigations were conducted to understand the role of the intestinal circulation in response to naturally occurring vasoactive substances, to drugs, to shock states and to increases in either intestinal motor activity or tension of the gut wall. In addition, the hydrodynamics of a diarrheal model were studied. Primary methods employed included use of anesthetized dogs and monkeys, measurement of mesenteric blood flow, gut and blood preessures with implanted flow or pressure transducers, intraarterial infusion of a variety of vasoactive agents and measurement of tissue enzymes by isotopic methods.
- Medicine and Medical Research