Accession Number:

ADA634965

Title:

Gonadotropin Pulsatllity in FemaIe Long Distance Runners

Descriptive Note:

Doctoral thesis

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD

Personal Author(s):

Report Date:

1986-10-24

Pagination or Media Count:

251.0

Abstract:

With the increased popularity of endurance athletics among women, exercise-associated menstrual irregularities have become more common. The object of this study was to determine whether eumenorrheic EU runners demonstrate any degree of abnormality in pulsatile gonadotropin release when compared to EU sedentary controls and to identify changes that could signal disruption of normal menstrual cyclicity. Gonadotropin pulsatility was measured by taking venous samples every fifteen minutes for six hours in age and weight matched endurance athletes N10 and sedentary controls N9 during early follicular phase. Athletes performed a one hour treadmill run at 75 of maximum oxygen consumption immediately followed by a second six hour gonadotropin pulsatility assessment. Data collected on all subjects included a maximum EKG treadmill test, body fat analysis, and determination of serum progesterone P, estradiol E2, testosterone T, cortisol C, and Beta-endorphin B-end concentrations.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE