Comparative Studies of Estrous Synchronization, Ovulation Induction, Luteal Function and Embryo Cryopreservation in Domestic Sheep and Application to Related Nondomestic Ungulate Species
UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
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The general hypothesis of this investigation is that domestic sheep can serve as valuable research models for developing, applying and comparatively examining conventional and new embryo biotechniques which can be integrated toward the preservation of related nondomestic species. A series of projects focused on 1 analyzing the effects of various hormonal ovulation induction procedures on ovarian function and the production of transferable quality embryos 2 determining whether atraumatic embryo collectiontransfer procedures could be developed and efficiently applied without compromising subsequent fertility and 3 evaluating novel cryoprotective solutions and cooling procedures for cryopreserving embryos. In Project I, it was determined that the number of corpora lutea CL and transferable quality embryos was greater P0.05 in follicle stimulating hormone FSH-P- and human menopausal gonadotropin hMG-treated sheep than in pregnant mares serum gonadotropin PMSG-treated ewes. However, regardless of the type of gonadotropin treatment, a high proportion 40 of ewes experienced premature luteal regression which was associated with embryo collection failure.
- Anatomy and Physiology
- Medicine and Medical Research