Accession Number:

ADA634084

Title:

The Role of Pituitary Beta-Endorphin in the Attenuation of Nociception

Descriptive Note:

Doctoral thesis

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD

Personal Author(s):

Report Date:

1986-08-28

Pagination or Media Count:

253.0

Abstract:

This research project examined the relationship between pituitary beta-endorphin B-END levels and pain in both humans and animals. The clinical trials examined this relationship through pharmacological interventions, both stimulatory and inhibitory, on release of pituitary B-END in patients prior to the onset of acute post-operative pain. Experiments using laboratory animals further investigated this relationship through interventions of both endocrine and opiate activity.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE