Identification of the srtC1 Transcription Start Site and Catalytically Essential Residues Required for Actinomyces oris T14V SrtC1 Activity
ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX
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In Actinomyces oris T14V, sortase SrtC1 mediates the assembly of type 1 fimbriae. We analyzed the effects of the conserved residues H184, H204, F213, Y236, L263, T265, C266 and R275 on the SrtC1 activity by site directed mutagenesis.