Accession Number:

ADA629425

Title:

Contribution of Bacterial and Viral infections to Attributable Mortality in Patients with Severe Burns: An Autopsy Series

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2010-01-01

Pagination or Media Count:

8.0

Abstract:

Bacterial infections are a common cause of mortality in burn patients and viral infections, notable herpes simplex virus HSV and cytomegalovirus CMV have also been associated with mortality. This study is a retrospective review of all autopsy reports from patients with severe thermal burns treated at the US Army Institute of Research USAISR burn unit over 12 years. The review focused on those patients with death attributed to a bacterial or viral cause by autopsy report. Of 3751 admissions, 228 patients died with 97 undergoing autopsy. Death was attributed to bacteria for 27 patients and to virus for 5 patients. Bacterial pathogens associated with mortality included Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. This association with mortality was independent of total body surface area burn, full thickness burn, inhalation injury and day of death post burn.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE