Accession Number:

ADA629394

Title:

Comparison of Development of Heterotopic Ossification in Injured US and UK Armed Services Personnel with Combat-Related Amputations: Preliminary Findings and Hypotheses Regarding Causality

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2010-07-01

Pagination or Media Count:

8.0

Abstract:

Background Recent reports have documented the rate of heterotopic ossification HO formation in the residual limbs of combat-related amputees from the US Armed Forces injured in Operations Iraqi and Enduring Freedom. Final amputation level within the zone of injury and blast as the mechanism of injury were identified as possible risk factors for the occurrence and grade of HO. There has been no previous description of HO in combat-related amputees from the UK service personnel. The purpose of this study was to examine potential differences in the prevalence of HO between UK and US Allied Forces, with particular attention to these risk factors, patient exposures, and any treatment differences between these two groups. Methods We reviewed the medical records and radiographs of 35 combat- related amputations from the UK and contrasted them with 213 previously reported amputations in US military personnel. We evaluated prevalence and severity of residual limb HO, Injury Severity Score ISS, the mechanism and zone of injury, type and level of amputation, number of debridements, method of wound irrigation, presence of severe head injury andor burns injury, use of topical negative pressure therapy and pulse lavage, number of days until wound closure, type of closure, and subsequent infections. All patients had a minimum of 2-month posthospital discharge radiographic follow-up. Comparisons were made using Fisher s exact, one-way analysis of variance, and x2 analysis.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Weapons Effects (Biological)
  • Military Forces and Organizations

Distribution Statement:

APPROVED FOR PUBLIC RELEASE