Accession Number:
ADA627935
Title:
A New Therapeutic Paradigm for Breast Cancer Exploiting Low Dose Estrogen-Induced Apoptosis
Descriptive Note:
Annual rept. 1 Sep 2011-18 May 2012
Corporate Author:
GEORGETOWN UNIV WASHINGTON DC
Personal Author(s):
Report Date:
2012-06-01
Pagination or Media Count:
322.0
Abstract:
The purpose of the CoE is to discover the molecular mechanisms and the modulation of estrogen-induced apoptosis. The laboratory research project is focused on genomics nad proteomics with a current focus on molecular interrogation to decipher mechanisms that may be applied to aid patient treatment. In parallel, but not supported by the CoE, is a pilot clinical study of estrogen-induced apoptosis in patients with metastatic breast cancer, that have had repeated cycles of successful antihormone therapy, but have subsequently failed and relapsed.
Descriptors:
Subject Categories:
- Medicine and Medical Research