Accession Number:

ADA626731

Title:

Infinite Coordination Polymer Nano- and Micro-Particles

Descriptive Note:

Final rept. 15 Jun 2011-14 Mar 2015

Corporate Author:

NORTHWESTERN UNIV EVANSTON IL

Personal Author(s):

Report Date:

2015-06-12

Pagination or Media Count:

27.0

Abstract:

Infinite coordination polymer ICP particles and metal-organic frameworks MOFs are attractive materials for a diverse array of applications, namely, catalysis, gas storage, chemical separations, photonics, and detections systems. Although promising, these micro- and nano-materials possess certain shortcomings that require further examination through fundamental studies. Towards overcoming these shortcomings, we proposed to investigate and drastically improve upon a series of key properties, specifically size and shape control, surface functionalization, volumetric surface area, and chemically specific gas sorption. Through these efforts, we have made significant discoveries, leading to the realization of biomolecule-functionalized nano-ICPs, unprecedentedly robust MOF topologies, and unique MOF structures with significant hydrogen and methane adsorption properties. Specifically, the novel DNA-ICP conjugates realized herein have demonstrated their utility as an in vitro gene regulatory tool, lending this construct to potential applications in therapeutics and diagnostics. Additionally, the carborane-MOF and MOP constructs described herein possess unique structural properties, making them key candidates for applications in selective gas sorption and boron neutron capture therapy BNCT.

Subject Categories:

  • Biochemistry
  • Physical Chemistry
  • Polymer Chemistry
  • Miscellaneous Materials

Distribution Statement:

APPROVED FOR PUBLIC RELEASE