Accession Number:

ADA626588

Title:

Discovery of FDA-Approved Drugs that Promote Retinal Cell Survival or Regeneration

Descriptive Note:

Annual rept. 15 Sep 2014-14 Sep 2015

Corporate Author:

JOHNS HOPKINS UNIV BALTIMORE MD

Report Date:

2015-10-01

Pagination or Media Count:

24.0

Abstract:

Ocular trauma due to blast or blunt forces affect millions of people worldwide, which often result in an irreversible loss of visual function. However, therapeutic approaches that can reverse this process or promote protection are limited. Recently, research on the damaged zebrafish retina has highlighted the potential of the Muller glia MG cells to function as a retinal stem cell to regenerate lost neurons. It is now appreciated that MG cells may retain the potential for retinal repair across vertebrate species, including humans.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE