Accession Number:

ADA626545

Title:

Emotion Regulation Training for Treating Warfighters with Combat-Related PTSD Using Real-Time fMRI and EEG-Assisted Neurofeedback

Descriptive Note:

Annual rept. 30 Sep 2014-29 Sep 2015

Corporate Author:

LAUREATE INST FOR BRAIN RESEARCH TULSA OK

Personal Author(s):

Report Date:

2015-10-01

Pagination or Media Count:

34.0

Abstract:

PTSD is a chronic and disabling condition . Neurocircuitry - based models of PTSD emphasize dysregulation of the amygdala, which is involved in the regulation of PTSD - relevant emotions. We are utilizing real - time functional magnetic resonance imaging neurofeedback rtfMRI - nf training with concurrent electroencephalography EEG recordings to directly target and modulate the emotion regulation neurocircuit. By using multimodal data, we ca n determine which EEG signalsleads or their combination specifically predicts or correlates with clinical improvement associated with the rtfMRI - nf training. Difficult recruitment is the main reason behind the delayed study schedule currently 12 months n o cost extension. During year 3 of the project we have improved our recruitment and are now finishing rtfMRI - nf and EEG data collection. Preliminary data analysis indicates amygdala training with concurrent EEG recordings in a combat - related PTSD population is feasible, and this procedure resulted in improvements in PTSD symptoms. We identified the variations in frontal upper alpha EEG asymmetry FEA during the rtfMRI - nf amygdala training as a promising measure of PTSD severity and treatment response. We will employ this measure together with our already developed stand - alone EEG - only neurofeedback training protocol to evaluate FEA EEG - nf training feasibility in combat - related PTSD.

Subject Categories:

  • Psychology
  • Medicine and Medical Research
  • Military Forces and Organizations

Distribution Statement:

APPROVED FOR PUBLIC RELEASE