Meditation for Depression: A Systematic Review of Mindfulness-Based Cognitive Therapy for Major Depressive Disorder
RAND NATIONAL DEFENSE RESEARCH INST SANTA MONICA CA
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Depression is a prevalent psychological health condition and clinical diagnoses such as major depressive disorder MDD are associated with significant burden in terms of reduced quality of life, lower productivity, increased prevalence of other conditions and increased health care costs. Several meditation approaches including mindfulness-based cognitive therapy MBCT have shown promise in the treatment of depression and the prevention of relapse. We conducted a systematic review of randomized controlled trials RCTs that assessed the efficacy and safety of MBCT for the treatment of patients diagnosed with MDD. We searched the databases PubMed, CINAHL, PsycINFO, Web of Science, Embase, CDSR, CENTRAL, DARE, clinicaltrials.gov, and PILOTS for English language RCTs published to January 2015. Two independent reviewers screened retrieved publications using a set of inclusion and exclusion criteria, abstracted study level data and assessed the quality of included studies. Meta-analysis was performed using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using GRADE.
- Medicine and Medical Research