Accession Number:

ADA626001

Title:

Low Ultraviolet B and Increased Risk of Brain Cancer: An Ecological Study of 175 Countries

Descriptive Note:

Technical rept. 1980-2008

Corporate Author:

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Report Date:

2009-07-01

Pagination or Media Count:

36.0

Abstract:

The purpose of this study was to determine whether an inverse association exists between latitude, solar ultraviolet B UVB irradiance, modeled 25-hydroxyvitamin D 25OHD levels, and incidence rates of cancer of the brain. Incidence rates of brain cancer were higher at higher latitudes R2 for males 0.45, p0.0001 females R2 0.35, p 0.0001. After adjustment for potential confounders, UVB irradiance p0.0001 and modeled serum 25 OHD were inversely associated with incidence rates. Countries with low solar UVB irradiance and estimated mean serum 25OHD levels generally had higher age-standardized incidence rates of brain cancer. Since this was an ecological study, further research would be worthwhile of the association of prediagnostic serum 25OHD with incidence rate in studies of cohorts of individuals.

Subject Categories:

  • Medicine and Medical Research
  • Optics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE