Accession Number:

ADA625995

Title:

Meningococcal Polysaccharide Vaccine Failure in a Patient with C7 Deficiency and a Decreased Anticapsular Antibody Response

Descriptive Note:

Journal article

Corporate Author:

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Report Date:

2012-05-01

Pagination or Media Count:

7.0

Abstract:

This is a case report of a military service member who received the meningococcal vaccine but died of the disease 15 months later. He had terminal complement component deficiency TCCD, and his anti-capsular antibody levels were inadequate. This case highlights the fact that some individuals with TCCD have an impaired or short-lived response to vaccination with meningococcal capsular polysaccharide, and it underscores the appropriateness of an initial two-dose series.

Subject Categories:

  • Microbiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE