Accession Number:

ADA624375

Title:

GC-MS/MS Analyses of Biological Samples in Support of Developmental Toxic Effects on Subcutaneous Exposure of Rats to GB

Descriptive Note:

Final rept. Jul 2012-Jan 2015

Corporate Author:

ARMY EDGEWOOD CHEMICAL BIOLOGICAL CENTER APG MD RESEARCH AND TECHNOLOGY DIR

Report Date:

2015-11-01

Pagination or Media Count:

38.0

Abstract:

This report documents the results of gas chromatography tandem mass spectrometry analyses of blood, tissues, and organs heart, lung, liver, kidney, brain, eye, and diaphragm that were obtained from rats postnatal days 7, 14, 21, 42, and 70 after their exposure to various concentrations of sarin GB via subcutaneous injection. The amounts of free and regenerated GB present in these biological samples were quantified using chemical ionization mass spectrometry with isotope dilution.

Subject Categories:

  • Biology
  • Anatomy and Physiology
  • Medicine and Medical Research
  • Toxicology
  • Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE