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Crozer-Chester Medical Center Burn Research Project

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Addendum to final rept. 19 Aug 2012-18 Jul 2013

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The Crozer Burn Treatment Center has been under contract with the U.S. Army Institute for Surgical Research in conjunction with the Army Burn Center since 2007 to carry out two studies under protocols established by Army researchers. Study 1 is Automated Fluid Resuscitation of Burn Patients. Study 2 is Evaluation of Aquacel Ag for Autogenous Skin Donor Sites. Study 1 We completed enrollment of 11 patients after screening 1,285 patients since January 2011. All study-related data has been transmitted to the USAISR for analysis. By entering these patients into the larger data collection project, this project has contributed to the Armys development of the next stages of Closed-Loop fluid resuscitation that will automatically titrate fluid therapy to changes in urinary output. We found that the use of the decision support system resulted in staff being more conscious of their fluid resuscitation efforts. Use of the digital urimeter allowed for more accurate urine output measurements. The Ab-Viser was an excellent tool for measuring bladder pressure. This technology will improve outcomes for returning military burn patients by providing guidance to providers on best practices. Study 2 During the entire period, which began in March 2009, a total of 2,136 patients were screened. 34 patients were enrolled and 29 completed the study. Study 2 is now complete. This study was presented as a poster at the 2013 ABA annual meeting. This study contributed to knowledge regarding use of Aquacel Ag as a dressing for autogenous skin donor sites compared to current standard donor site care in the injured burn patient. The study is important to soft tissue trauma and burn research because expediting wound healing helps return injured service members to full military duty. The study found that Xeroform usual care was the preferred topical wound dressing when compared to Aquacel Ag, which contradicted the study hypothesis. A manuscript is currently bein

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  • Medicine and Medical Research

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