Accession Number:

ADA624271

Title:

Complement and Immunoregulation in Tissue Injury

Descriptive Note:

Annual rept. 30 Sep 2013-29 Sep 2014

Corporate Author:

BETH ISRAEL DEACONESS MEDICAL CENTER BOSTON MA

Personal Author(s):

Report Date:

2014-10-01

Pagination or Media Count:

13.0

Abstract:

Our goal is to ultimately enable the development of novel therapeutic agents and strategies to ameliorate tissue injury in IR related conditions. Preliminary findings suggested a role for Il-17 IL-23 axis in ischemia reperfusion injury which we have continued to study. We have shown that by depleting IL-17 and IL-23 tissue injury is alleviated.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE