Accession Number:

ADA621838

Title:

Study of the Neurophysiology of Central Fatigue

Descriptive Note:

Final rept. 1 Jul 2010-30 Jun 2014

Corporate Author:

COLORADO UNIV AT DENVER

Personal Author(s):

• Kluger, Benzi
• Ding, Mingzhou
• Rojas, Donald
• Krupp, Lauren
• Enoka, Roger

Report Date:

2014-11-05

Pagination or Media Count:

7.0

Abstract:

Specific Aims 1 To identify and characterize the functional neuroanatomic networks most strongly correlated with objective cognitive fatigue using event related potentials ERPs. 2 To determine the neurophysiologic mechanisms underlying objective cognitive fatigue using the variable signal plus ongoing activity VSPOA model. 3 To investigate the relationship of GABAergic and glutamatergic neural transmission to objective cognitive fatigue and network pathology.

Descriptors:

• *FATIGUE(PHYSIOLOGY)
• *NERVE TRANSMISSION
• *NEUROPHYSIOLOGY
• BEHAVIOR
• COGNITION
• CORRELATION
• INFORMATION PROCESSING
• NETWORK ARCHITECTURE
• NEURAL NETS
• PATHOPHYSIOLOGY
• PERFORMANCE(HUMAN)
• PSYCHOMOTOR FUNCTION
• REACTION TIME
• RESPONSE(BIOLOGY)
• SIGNAL PROCESSING

Subject Categories:

• Psychology
• Medicine and Medical Research
• Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE