Accession Number:

ADA621297

Title:

Temporal Progression of Visual Injury from Blast Exposure

Descriptive Note:

Annual rept. 1 Sep 2012-31 Aug 2013

Corporate Author:

UTAH UNIV SALT LAKE CITY

Personal Author(s):

• Coats, Brittany
• Shedd, Daniel

Report Date:

2013-09-01

Pagination or Media Count:

18.0

Abstract:

The purpose of this grant is to investigate the temporal progression of eye injury from blast exposure and identify early predictors of visual dysfunction. We propose to accomplish this by first identifying the probability of military personnel developing visual system injury after blast exposure, and determining the time point after blast exposure that visual system injury becomes identifiable. Next, we propose to systematically evaluate the time course of visual system injury from blast exposure using our existing rat model for blast traumatic brain injury. From the studies performed in the previous year, we have found that low-level blast exposure 225 kPa in rats appears to result in a general decrease in visual acuity without any signs of stress or pain in the animals. Scleral hemorrhage was observed upon gross exam.

Descriptors:

• *EYE
• *TRAUMA
• *WOUNDS AND INJURIES
• BIOMECHANICS
• BLAST
• DIAGNOSIS(MEDICINE)
• HEMORRHAGE
• PREDICTIONS
• RATS
• SIGNS AND SYMPTOMS
• VISUAL ACUITY

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE