Accession Number:

ADA618971

Title:

Use of Ultra Rapid Opioid Detoxification in the Treatment of US Military Burn Casualties

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2011-07-01

Pagination or Media Count:

7.0

Abstract:

Background The purpose of this case series was to review the management of burn patients who requested ultrarapid opioid detoxification under anesthesia after extended duration of narcotic use for chronic pain related to burn injury. Methods The treatment plan of six opioid-dependent burn patients was analyzed to assess the effectiveness of our detoxification practice to date. Demographic and clinical information was used to characterize the patient population served age, burn size, injury severity, duration of narcotic use before detoxification intervention, and length of hospitalization stay. Daily narcotic consumption, in morphine equivalent units, was noted both before and after detoxification. Results Six burn patients average age, 31 years underwent detoxification at the Burn Center during a hospitalization lasting between 1 day and 2 days. Average burn size was 38 total body surface area range, 17 65 average Injury Severity Score was 30 range, 25 38. Mean duration of narcotic use was 672 days range, 239 1,156 days average use of narcotics at time of detoxification was 200 units daily. Mean outpatient consumption for opioids after the intervention was minimal 25 unitsd. No complications were noted during any procedures. Conclusions The results of ultrarapid opioid detoxification under anesthesia suggests that it is safe and effective for treating opioid addiction in military burn casualties when a coordinated, multidisciplinary approach is used. Safety and effectiveness to date validate current practice and supports incorporation into clinical practice guidelines. Further clinical research is warranted to identify those patients who may benefit most from detoxification and to determine the timing of such treatment.

Subject Categories:

  • Medicine and Medical Research
  • Toxicology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE