Tolerance to Central Hypovolemia: The Influence of Oscillations in Arterial Pressure and Cerebral Blood Velocity
ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX
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Higher oscillations of cerebral blood velocity and arterial pressure AP induced by breathing with inspiratory resistance are associated with delayed onset of symptoms and increased tolerance to central hypovolemia. We tested the hypothesis that subjects with high tolerance HT to central hypovolemia would display higher endogenous oscillations of cerebral blood velocity and AP at presyncope compared with subjects with low tolerance LT. One-hundred thirty-five subjects were exposed to progressive lower body negative pressure LBNP until the presence of presyncopal symptoms.
- Anatomy and Physiology
- Medicine and Medical Research