Accession Number:

ADA618417

Title:

Expression of Proteins Involved in Epithelial-Mesenchymal Transition as Predictors of Metastasis and Survival in Breast Cancer Patients

Descriptive Note:

Final summary rept. 1 Nov 2010-31 Oct 2014

Corporate Author:

HEALTH RESEARCH INC BUFFALO NY

Report Date:

2015-01-01

Pagination or Media Count:

31.0

Abstract:

The purpose of this research is to investigate protein expression and promoter region DNA methylation status of six genes involved in epithelial-mesenchymal transition in relation to breast cancer lymph node metastasis, recurrence, and survival. Breast tumor tissue has been retrospectively identified from the Pathology Resource and immunohistochemical staining for all proteins has been completed. Scoring and analysis of IHC assays is ongoing. FFPE tissue cores for a subset of the IHC-stained tissues have been procured for isolation of DNA and methylation assay.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE