Accession Number:

ADA616874

Title:

Quantitative Analysis, Design, and Fabrication of Biosensing and Bioprocessing Devices in Living Cells

Descriptive Note:

Final rept. 1 Jun 2014-31 May 2015

Corporate Author:

MASSACHUSETTS INST OF TECH CAMBRIDGE

Personal Author(s):

• Del Vecchio, Domitilla

Report Date:

2015-03-10

Pagination or Media Count:

8.0

Abstract:

The objective of this research is to develop quantitative techniques for the de novo design and fabrication of biosensing devices in living cells. Such devices will be entirely composed of bio-molecular building blocks extracted from living organisms and re-engineered for enhanced functionality. These biosensing devices will be able to reproduce themselves, will be both far smaller and significantly cheaper than current nanoscale electronic devices, and will have the capacity for complex computations.

Descriptors:

• *BIOLOGICAL DETECTION
• *CELLS(BIOLOGY)
• *SYNTHETIC BIOLOGY
• CIRCUITS
• CONTROL THEORY
• DYNAMICS
• ESCHERICHIA COLI
• FABRICATION
• FEEDBACK
• INVERTERS
• NOISE(RADIO)
• PHOSPHORYLATION
• QUANTITATIVE ANALYSIS

Subject Categories:

• Genetic Engineering and Molecular Biology
• Miscellaneous Detection and Detectors

Distribution Statement:

APPROVED FOR PUBLIC RELEASE