Accession Number:

ADA615544

Title:

Disruption of Calcium Homeostasis during Exercise as a Mediator of Bone Metabolism

Descriptive Note:

Annual rept. 30 Sep 2013-29 Sep 2014

Corporate Author:

COLORADO UNIV AURORA CO

Personal Author(s):

Report Date:

2014-10-01

Pagination or Media Count:

12.0

Abstract:

Batched analysis of serumswear samples from EXP1, regulatory approvals from EXP2, protocol amendments, and generation of forms were completed in Q1-4. Completion of 3 successful clamps occurred in October 2013EXP2-pilot and EXP2 enrollment was initiated. Thereafter, the major goals for Year 2 were to complete approximately one-half of the Experiment 2 Study EXP2 and obtain regulatory approval from the EXP3-pilot. Approval of the Continuing Review application, which included the expanded description of EXP3-pilot, was received 28 Aug 2014. Isotopes for the protocol were ordered delivery occurred 20 Oct 2014. A revised SOW for EXP3-pilot was submitted 10 Jun 2014 but an amended contract has not yet been received. We expect EXP3-pilot to begin in Q1 of Year 3. Wendy Kohry, PhD, presented the full data on calcium disruption data from EXP1 at the 2014 Military Health System Research Symposium Appendix A and Vanessa Sherk, PhD, presented partial data from EXP1 at the 2014 American College of Sports Medicine Annual Meeting Appendix B.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE