Accession Number:

ADA615221

Title:

Biological Activities of Fusarochromanone: a Potent Anti-cancer Agent

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2014-09-03

Pagination or Media Count:

12.0

Abstract:

Fusarochromanone FC101 is a small molecule fungal metabolite with a host of interesting biological functions, including very potent anti-angiogenic and direct anti-cancer activity. Our data presented here indicates that FC101 is an excellent lead candidate for small molecule anti cancer agent that simultaneously affects angiogenesis signaling, cancer signal transduction, and apoptosis. further understanding of the underlying FC101s molecular mechanism may lead to the design of novel targeted and selective therapeutics, both of which are pursued targets in cancer drug discovery.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE