Systemic Review and Meta-analysis of Randomized Clinical Trials Comparing Primary vs Delayed Primary Skin Closure in Contaminated and Dirty Abdominal Incisions
ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX
Pagination or Media Count:
Surgical site infection SSI following abdominal surgery is common. When assessed actively and prospectively, it has been found to affect as many as 45 of patients. Furthermore,without active post discharge surveillance, up to 79 of SSI will be missed. Surgical site infection confers significant morbidity,with an additional risk of mortality. There are further health care related costs, through increased hospital stay, repeated surgery, nursing care costs, and drug treatment. Because of these factors, there is international interest in reducing the rate of SSI. To determine using meta-analysis whether delayed primary skin closure DPC of contaminated and dirty abdominal incisions reduces the rate of surgical infection compared with primary skin closure PC. Delayed primary skin closure may reduce the rate of SSI, but current trials fail to provide definitive evidence based on poor design. Well-designed, large-numbered randomized clinical trials are warranted.
- Anatomy and Physiology
- Medicine and Medical Research