Accession Number:

ADA615216

Title:

Anatomical Manifestations of Primary Blast Ocular Trauma Observed in a Postmortem Porcine Model

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2014-02-01

Pagination or Media Count:

10.0

Abstract:

We qualitatively describe the anatomic features of primary blast ocular injury observed using a postmortem porcine eye model. Porcine eyes were exposed to various levels of blast energy to determine the optimal conditions for future testing. Evidence for primary blast injury was obtained. While some of the damage was observed in the control eyes, the incidence and severity of this damage in exposed eyes increased with impulse and peak pressure, suggesting that primary blast exacerbated these injuries. Common findings included angle recession, internal scleral delamination, cyclodialysis, peripheral chorioretinal detachments, and radial peripapillary retinal detachments. No full thickness openings of the eyewall were observed in any of the eyes tested. Scleral damage demonstrated the strongest associative tendency for increasing likelihood of injury with increased overpressure. These data provide evidence that primary blast alone in the absence of particle impact can produce clinically relevant ocular damage in a postmortem model. The blast parameters derived from this study are being used currently in an in vivo model. We propose a Cumulative Injury Score indicating the clinical relevance of observed injuries.

Subject Categories:

  • Biology
  • Medicine and Medical Research
  • Weapons Effects (Biological)

Distribution Statement:

APPROVED FOR PUBLIC RELEASE