Patient-based Outcomes and Quality of Life after Salvageable Wartime Extremity Vascular Injury
ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX
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Objective To date, contemporary studies on wartime vascular trauma have focused on acute management strategies and early results, with no characterization of enduring functional limb salvage or its relation to quality of life. The objective of this study was to describe long-term, patient-based quality of life and function after extremity vascular injury EVI. Methods The Joint Theater Trauma Registry was queried for U.S. troops with EVI. Injury and management data was obtained and the Medical Outcomes Study Short Form 36 SF-36 Health Survey administered after patient contact and consent. Demographic, injury, and management variables were analyzed and examined for correlation with the primary end points of favorable or unfavorable outcome defined by SF-36 Mental MCS or Physical Component Summary PCS scores of 42 or 42 effect size 0.8. Results Surveys were completed by 214 patients, who were a median age of 25 years range, 19-52 years. The Injury Severity Score was 15.3 6 8.6 and the Mangled Extremity Severity Score was 5.65 6 1.4. Amputation-free survival was 84 at mean follow-up of 61 6 24 months. Overall SF-36 PCS and MCS scores were 43.0 6 9.2 and 46.6 6 12.4, respectively, with 92 respondents 43 reporting favorable outcomes on both MCS and PCS. On multivariate analysis, older age, severe extremity injury Mangled Extremity Severity Scores 7, and chronic pain were predictive of unfavorable physical outcomes P .05. Presence of pain, nerve injury, and junior rank E7 were predictive of unfavorable MCS scores P .05. Higher educational background baccalaureate or above was associated with favorable outcome P .05. Conclusions This study reports the first long-term patient-centered outcomes data after wartime EVI. At 5 years after injury, quality-of-life measures are reduced compared with national norms.
- Medicine and Medical Research