Accession Number:

ADA614563

Title:

Experience with the Use of Hemopure in the Care of a Massively Burned Adult

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2014-03-01

Pagination or Media Count:

5.0

Abstract:

Objective To report the use of a bovine hemoglobin-based oxygen carrier HBOC-201 in an elderly patient sustaining extensive thermal injury unable to receive allogenic transfusion due to religious preference. Methods Case report and literature review describing steps required for acquisition and safe infusion of HBOC-201. Results Six units of HBOC-201 were infused in the perioperative period for anemia with signs of critically low oxygen delivery without adverse sequelae. The patient ultimately died as a result of multiple organ failure. Conclusions Despite disappointing results of the use of HBOCs in other patient populations, there is a role for compassionate, emergency use of cell-free hemoglobin in the management of burn patients unable to receive allogenic blood products.

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE