Accession Number:

ADA614246

Title:

Predicted Hematologic and Plasma Volume Responses Following Rapid Ascent to Progressive Altitudes

Descriptive Note:

Technical rept.

Corporate Author:

ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA THERMAL AND MOUNTAIN MEDICINE DIVISION

Report Date:

2014-06-01

Pagination or Media Count:

36.0

Abstract:

Scientific consensus does not exist regarding hematological responses to moderate to high altitude exposure. The purpose of this study was to quantify the expected changes in hemoglobin concentration Hb, hematocrit Hct, and PV changes as a result of a given gain in terrestrial elevation, delineate the time course of these changes, and define baseline demographics and physiologic descriptors that are important in predicting these changes. The overall impact of altitude can be summarized using the following correction factors 1 0.1gdl increase in Hb for every 500 m increase in altitude regardless of gender, 2 1.1 increase in Hct at 2000 m with an additional 2-6 increase for every 500 m increase in altitude depending non the altitude, and 3rapid 5 loss in PV at 2000 m and additional 0.6 decrease with every 500 m above 2000 m. It is anticipated that results will enhance the ability of sport organizations to detect blood doping in athletes seeking to gain an edge in their athletic performance.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE