Cavitation Induced Structural and Neural Damage in Live Brain Tissue Slices: Relevance to TBI
Final rept. 1 Sep 2010-31 Aug 2014
FLORIDA UNIV GAINESVILLE DEPT OF MECHANICAL AND AEROSPACE ENGINEERING
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Cavitation-induced shock wave, as might occur in the head during exposure to blast waves, was investigated as a possible damage mechanism for soft brain tissues. A novel experimental scheme was developed to visualize and control single bubble cavitation and its collapse, and the influence of this process on a nearby tissue surrogate was investigated. The experiment utilized a Hopkinson pressure bar system which transmits a simulated blast pressure wave with over and under pressure components to a fluid-filled test chamber implanted with a seed gas bubble.
- Anatomy and Physiology
- Medicine and Medical Research
- Fluid Mechanics