Accession Number:

ADA612616

Title:

Cavitation Induced Structural and Neural Damage in Live Brain Tissue Slices: Relevance to TBI

Descriptive Note:

Final rept. 1 Sep 2010-31 Aug 2014

Corporate Author:

FLORIDA UNIV GAINESVILLE DEPT OF MECHANICAL AND AEROSPACE ENGINEERING

Personal Author(s):

Report Date:

2014-09-29

Pagination or Media Count:

45.0

Abstract:

Cavitation-induced shock wave, as might occur in the head during exposure to blast waves, was investigated as a possible damage mechanism for soft brain tissues. A novel experimental scheme was developed to visualize and control single bubble cavitation and its collapse, and the influence of this process on a nearby tissue surrogate was investigated. The experiment utilized a Hopkinson pressure bar system which transmits a simulated blast pressure wave with over and under pressure components to a fluid-filled test chamber implanted with a seed gas bubble.

Subject Categories:

  • Biology
  • Anatomy and Physiology
  • Medicine and Medical Research
  • Fluid Mechanics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE