Accession Number:

ADA612433

Title:

RBC Storage Effect on Coagulation, Microparticles and Microchimerism in Critically Ill Patients

Descriptive Note:

Annual rept. 27 Dec 2011-26 Dec 2012

Corporate Author:

BLOOD SYSTEMS INC SCOTTSDALE AZ

Report Date:

2013-01-25

Pagination or Media Count:

7.0

Abstract:

The study aims include investigating specific mechanisms of adverse effects related to RBC storage age in critically ill patients. We continue to enroll patients in this study. Thus far, we have enrolled 82 patients, from whom samples have been collected, processed, shipped from Canada to San Francisco. We have completed coagulation testing on 90 patients samples and HLA typing for 54 patients Day 0 samples so far. Optimization work for the microparticle studies have built on related NIH-funded studies of in vitro properties of microparticles, refining the list of activation markers to be tested. We have completed microparticle testing for 6 patients.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE