Feasibility of Prostate Cancer Diagnosis by Transrectal Photoacoustic Imaging
Final rept. 1 Mar 2011-28 Feb 2014
TEXAS UNIV AT ARLINGTON
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There is no effective imaging tool currently available for prostate cancer detection needle biopsy is the current practice for diagnosis of the disease, aiming randomly in the prostate. Transrectal ultrasound has been used as a guiding tool to direct tissue needle biopsy for prostate cancer diagnosis it cannot be utilized for detecting prostate cancer due to lack of sensitivity. Recent studies show that the combination of light and ultrasound may lead to a new imaging device that can be used to provide cancer-sensitive, ultrasound images for prostate cancer detection. The goal of this study is to examine a new idea that combination of light and sound can lead to a better medical device so that doctors can clearly see harmful cancerous areas in the human prostate. The scientific basis for this idea is that when an organ is illuminated with light, cancer tissue will absorb more light and generate some heat. The light-generated heat, in turn, will be converted to sound wave and be heard by sound detectors. The cancerous sound waves will be plotted into images, allowing doctors see cancer better in the human prostate. The plan for the study includes two steps 1 to setup the device and perform laboratory experiments using non-tissue samples, and 2 to calculate the measured data and thus to prove the new idea.
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